Polysialic Acid-N-Trimethyl Chitosan Nanoparticles for Oligonucleotide Delivery
نویسندگان
چکیده
296 ©2013 Society For Biomaterials
منابع مشابه
Immunomodulation of cystic fibrosis epithelial cells via NF-κB decoy oligonucleotide-coated polysaccharide nanoparticles.
Activation of the transcription factor nuclear factor-kappa B (NF-κB) signaling pathway is associated with enhanced secretion of pro-inflammatory mediators and is thought to play a critical role in diseases hallmarked by inflammation, including cystic fibrosis (CF). Small nucleic acids that interfere with gene expression have been proposed as promising therapeutics for a number of diseases. How...
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